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OP-LENS — PMMA Intraocular Lens | Agaaz Ophthalmics
PMMA INTRAOCULAR LENS

OP-LENS

The world's most proven IOL material — engineered for surgeons who value crisp optics, capsular-bag stability, and six decades of unmatched clinical trust. Sometimes, the original is still the best.

Material: PMMA
Diopters: +5.0D to +30.0D
RI: 1.42
Options: Clear & Yellow
OP-LENS PMMA intraocular lens
Clear option
Yellow option
60+ year material legacy
THE PMMA ADVANTAGE

Why the world still trusts PMMA.

PMMA (polymethyl methacrylate) was the first material ever implanted inside a human eye — and it remains the most widely implanted IOL material globally by cumulative volume. Here's why it endures.

Zero water absorption

Unlike hydrophilic acrylic which absorbs 18–38% water, PMMA absorbs essentially none. This means zero osmotic swelling, zero calcification risk, and stable optics from day one through decade ten.

Superior optical clarity

PMMA's refractive index of 1.42 and glass-like transparency deliver crisp, high-contrast vision. Studies note PMMA consistently produces excellent visual acuity outcomes comparable to modern foldable lenses.

Dimensional stability

PMMA doesn't swell, warp, or change shape inside the eye. The lens you implant is the lens the patient lives with — no surprises. Its rigidity means predictable vault height and centration.

Biocompatibility proven over 60+ years

Sir Harold Ridley implanted the first PMMA IOL in 1949. Since then, hundreds of millions of PMMA lenses have been implanted worldwide. No other IOL material has a longer in-vivo safety track record.

Lower PCO rates than hydrophilic

Multiple studies report lower posterior capsule opacification (PCO) rates with rigid PMMA IOLs compared to hydrophilic acrylic IOLs. Apple et al. (2001) and Nishi et al. documented PMMA's favorable PCO profile.

Cost-effective for high-volume programs

PMMA IOLs enable the highest-quality cataract surgery at the most accessible price point — critical for mass cataract blindness elimination programs worldwide.

Clinical evidence supporting PMMA

Published peer-reviewed literature consistently demonstrates that PMMA IOLs deliver excellent long-term outcomes:

Apple DJ et al. (2001) — Documented that PMMA IOLs show minimal long-term opacification and maintain optical clarity over decades. Survey of Ophthalmology.
Nishi O et al. (2004) — Compared PCO rates across materials; PMMA showed favorable capsule interaction compared to hydrophilic acrylic. J Cataract Refract Surg.
Schmidbauer et al. (2001) — Review of explanted IOLs showed PMMA lenses maintained structural integrity better than many newer materials. J Cataract Refract Surg.
WHO IAPB Vision Atlas (2020) — PMMA remains the recommended IOL material for high-volume cataract surgical programs in developing nations due to cost-effectiveness and proven outcomes.

Read our latest blog
PMMA vs Foldable IOL — Complete Clinical Comparison
A deep dive into when PMMA outperforms modern foldable lenses and why it remains clinically relevant.
PMMA FUN FACTS

The material that changed ophthalmology.

PMMA's history is as remarkable as its optics. Here are facts that most people in the industry don't know.

1949
First PMMA IOL implanted by Sir Harold Ridley at St Thomas' Hospital, London
300M+
Estimated cumulative PMMA IOLs implanted worldwide since 1949
0%
Water absorption — PMMA is completely hydrophobic with zero osmotic swelling
75 yrs
Longest known in-vivo PMMA IOL — still optically clear in a living patient

The Spitfire origin story

Sir Harold Ridley noticed that WWII Spitfire pilots who got PMMA canopy shards embedded in their eyes showed no inflammatory reaction — the body tolerated the plastic. This observation led to the invention of the intraocular lens. Every IOL implanted today traces its lineage to that battlefield observation.

PMMA in everyday life

PMMA isn't just in eyes — it's the material behind Plexiglass, aquarium panels, aircraft windows, dental prosthetics, and bone cement. Its optical clarity is why it's sometimes called "organic glass." The Louvre's protective barrier in front of the Mona Lisa? That's PMMA.

"When you choose PMMA, you're choosing the most clinically validated optical material in ophthalmic history. No other material has 75 years of continuous in-vivo data." — Agaaz Ophthalmics, Quality Engineering
THOUGHT EXPERIMENT

What if PMMA could fold?

Imagine a material with PMMA's zero water absorption, 1.42 refractive index, dimensional stability, and 75-year biocompatibility track record — but foldable enough to pass through a 2.2mm incision.

It would combine the best of both worlds: the predictability that made PMMA the gold standard for half a century, with the micro-incision workflow that modern surgeons prefer. Zero calcification risk. Zero osmotic instability. Perfect optics. Minimal PCO. And small-incision delivery.

That material doesn't exist yet — but it's the benchmark against which every new IOL polymer should be measured. Until then, for markets and programs where incision size is secondary to optical quality and long-term stability, PMMA remains unmatched.

TECHNICAL SPECIFICATIONS

OP-LENS specifications

ProductOP-LENS — PMMA IOL
MaterialPMMA (Polymethyl methacrylate)
Refractive index1.42
Diopter range+5.0D to +30.0D
Optic diameter5.5 mm / 6.0 mm
Overall diameter12.5 mm
PlacementPosterior chamber, capsular bag
OptionsClear & Yellow (blue-light filtering)
SterilizationEO sterilized
PackagingIndividual sterile blister pack
1.42
Refractive Index
0%
Water Absorption
5.5
Optic Diameter (mm)
12.5
Overall Diameter (mm)

PMMA material advantages

Optical clarity
94%
Dimensional stability
96%
Biocompatibility
92%
PCO resistance
85%
Cost efficiency
98%
MATERIAL COMPARISON

PMMA vs modern IOL materials.

An honest comparison. We manufacture all three — PMMA, hydrophilic, and hydrophobic — and recommend based on your market needs.

ParameterPMMA (OP-LENS)Hydrophilic AcrylicHydrophobic Acrylic
Incision size5.5–6.0 mm (SICS/ECCE)2.2–2.8 mm2.2–2.8 mm
Water absorption0%18–38%~0.5%
Calcification riskNoneDocumented casesVery low
PCO rateLowModerate–HighLow
GlisteningsNoneNonePossible
In-vivo track record75+ years~25 years~25 years
Cost per unitLowestModerateHighest
Best forSICS/ECCE, mass programs, cost-sensitive marketsPhaco, general cataractPhaco, premium cataract
Agaaz productOP-LENSOP-FOLD AS, i-NeraOP-VIEW AS
FAQ

Common questions.

Is PMMA still relevant with foldable IOLs available?
Absolutely. PMMA remains the most implanted IOL material globally by cumulative volume. For SICS and ECCE techniques — which are the primary surgical methods in many developing countries — PMMA is the gold standard. Its optical quality, stability, and cost-effectiveness make it irreplaceable for mass cataract surgery programs.
What diopter range is available?
OP-LENS is available from +5.0D to +30.0D in 0.5D steps. Both clear and yellow (blue-light filtering) options are available. Custom diopter requests can be discussed for large orders.
Does PMMA cause more inflammation than foldable IOLs?
Modern PMMA IOLs have excellent biocompatibility. While the larger incision can cause more initial inflammation compared to micro-incision phaco, the PMMA material itself has a 75-year safety record. Studies by Apple et al. confirm that PMMA triggers minimal chronic inflammatory response.
Is private labelling available for OP-LENS?
Yes. Agaaz Ophthalmics offers private labelling and OEM manufacturing for qualified distributors. Contact us with your country, estimated volumes, and brand requirements.
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